Both clinical and laboratory parameters were not predictive of CT findings. In this population of septic patients in medical intensive care, microbiological analysis complemented CT findings. There was no significant association between focus-positive CT scans and mortality ( p = 0.81).
In 81.6% ( n = 62/76), the CT findings resulted in one consequence, in 14.5% ( n = 11/76) in two consequences, and in 3.9% ( n = 3/76) in three consequences. In 33.5% ( n = 76/227) of cases, the CT findings had at least one therapeutic consequence. Among C-reactive protein (CRP), procalcitonin (PCT), and leukocytes, in focus-positive versus focus-negative CT scans, CRP showed a minor but statistically significant elevation in the group with focus-positive CT scans (OR = 1.004, 95% CI = 1.000–1.007, p = 0.04). Sequential organ failure assessment (SOFA) scores were slightly but nonsignificantly higher in patients with a focus-positive CT, odds ratio (OR) = 0.999 (95% CI 0.997–1.001) with p = 0.52.
There were no significant differences between focus-positive CT scans with regard to positive microbiological testing ( p = 0.32). ResultsĬT revealed more positive infectious foci 52.4% ( n = 191/227) than microbiological tests 39.3% ( n = 79/201). Statistical analysis was performed using nonparametric tests and logistic regression analysis. Clinical and laboratory information was gathered. Diagnostic accuracy of CT was compared to microbiological results. CT reports were categorized according to identified foci and their diagnostic certainty. Material and methodsĪ full-text search in the radiological information system (RIS) retrieved 227 body CT examinations conducted to identify infectious sources in 2018. To identify predictors of CT findings and patient outcomes in a population of septic patients from a medical ICU. However, international sepsis guidelines do not provide information on imaging choice. Sepsis is a life-threatening condition that requires immediate focus identification and control.
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